Symptoms of MIXED CONNECTIVE TISSUE DISEASE

Raynaud's phenomenon is a common symptom of this disorder. Here, there are changes in the color of the skin, particularly of the hands, when exposed to cold. Puffy hands, joint pain and muscle pain occur. Fever may develop. Eventually, there may be tight, shiny skin, particularly of the hands and feet. A rash may develop on the face and there may be increased sensitivity to the sunlight. Hair loss and ulcerations of the mouth may occur. Joint pain may become associated with joint stiffness and swelling. Deformity of the joints may occur. The muscles may become weakened, particularly those around the shoulders and hips. Chest pain and shortness of breath may develop. Difficult or painful swallowing may develop as well as acid reflux.