Symptoms of PERIPHERAL NEUROPATHY

Peripheral neuropathy usually produces symptoms that appear gradually and slowly progress. Most commonly, they produce tingling and numbness that begins in the hands and feet and progress inwards, towards the body. This type of sensory change is often described for its location, stocking and glove sensory changes. Frequently, the symptoms tend to be symmetric. Weakness of the involved muscles may occur. Pain in an extremity may occur, which is frequently worse at night. Loss of sensation may develop in the hands and feet. This can lead to unexpected injuries and burns, because the bodies natural defense systems are not intact. The involved areas of the skin often become dry and increasingly sensitive to touch. Unusual burning sensations in the area of sensory loss can occur. Some forms of peripheral neuropathy may affect the nerves that supply rectal, urinary and sexual function. This can lead to incontinence and the loss of sexual function, particularly in men. Some of these changes can be confused with diseases that affect the spine and spinal cord. Involvement of the sympathetic nervous system can also lead to problems with orthostatic hypotension. Here, the blood vessels cannot contract in response to changes in position and lowered blood pressure may occur.